Obesity, inflammation and metabolic disorders
نویسندگان
چکیده
منابع مشابه
Role of Inflammation in Obesity Related Metabolic Disorders
Globally, obesity is a major contributor to the burden of several chronic metabolic diseases, including type 2 diabetes mellitus and cardiovascular diseases. With changing life style, obesity has now become a global phenomenon affecting all socioeconomic groups, irrespective of age, sex or ethnicity. Morbid obesity and co morbidities of metabolic syndrome, such as hypertension, dyslipidemia and...
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Obesity is a major public health issue as it is causally related to several chronic disorders, including type-2 diabetes, CVD and cancer. Novel research shows that the gut microbiota is involved in obesity and metabolic disorders, revealing that obese animal and human subjects have alterations in the composition of the gut microbiota compared to their lean counterparts. Moreover, transplantatio...
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Eosinophils are potent effector cells implicated in allergic responses and helminth infections. Responding to stimuli, they release their granule-derived cytotoxic proteins and are involved in inflammatory processes. However, under homeostatic conditions, eosinophils are abundantly present in the intestine and are constantly in contact with the gut microbiota and maintain the balance of immune ...
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OBJECTIVE Inflammation is an important factor in the development of insulin resistance, type 2 diabetes, and fatty liver disease. As a member of the tumor necrosis factor receptor superfamily (TNFRSF9) expressed on immune cells, 4-1BB/CD137 provides a bidirectional inflammatory signal through binding to its ligand 4-1BBL. Both 4-1BB and 4-1BBL have been shown to play an important role in the pa...
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Since 1980, the global prevalence of obesity has doubled; in the United States, it has almost tripled. Billions of people are overweight and obese; the WHO reports that >65% of the world's population die of diseases related to overweight rather than underweight. Obesity is a complex disease that can be studied from "metropolis to metabolite"—that is, beginning at the policy and the population l...
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ژورنال
عنوان ژورنال: Indian Journal of Science and Technology
سال: 2008
ISSN: 0974-6846,0974-5645
DOI: 10.17485/ijst/2008/v1i4.8